What are the pathological effects of lethal dose of Phosgene? Write 2-3lines about its chemical nature.

Phosgene is a highly toxic chemical compound with the formula COCl2. It is a colorless gas at room temperature, with a pungent odor resembling that of freshly cut hay. Phosgene was widely used as a chemical warfare agent during World War I due to its ability to cause severe respiratory and pulmonary damage.

The pathological effects of a lethal dose of phosgene primarily involve its corrosive action on the respiratory system. Inhalation of phosgene gas can lead to acute lung injury, pulmonary edema, and respiratory failure. Phosgene reacts with water in the lungs to form hydrochloric acid, resulting in corrosive damage to the airway epithelium and alveolar tissues. This leads to inflammation, pulmonary edema, and impairment of gas exchange, ultimately causing respiratory distress and potentially fatal outcomes. Additionally, phosgene exposure can induce systemic effects such as cardiovascular collapse and multiorgan failure, further contributing to morbidity and mortality. Overall, phosgene poisoning represents a significant health threat, necessitating prompt medical intervention and supportive care to mitigate its devastating effects on exposed individuals.